The incidence and mortality of colorectal cancer have shown an upward trend in the past decade.Therefore, the prevention, diagnosis, and treatment of colorectal cancer still need our continuous attention.Finding compounds with strong anticancer activity and low toxicity is a good strategy for colorectal cancer (CRC) therapy.Trametes versicolor is a
One of the most critical safety issues concerning the transportation and the distribution of hazardous materials, is the possible occurrence of accidental fires affecting transport vessels, leading to the heat up and consequent failure with catastrophic effects.Therefore, since the early seventies, numerous field solo jec 10 studies and laboratory
A comprehensive analysis of crystallographic data of 565 high-resolution protein homodimers comprised of over 250,000 residues suggests discount greenery that amino acids form two groups that differ in their tendency to distort or symmetrize the structure of protein homodimers.Residues of the first group tend to distort the protein homodimer and ge
Abstract Feline infectious peritonitis (FIP) is a lethal, immune-mediated disease in cats caused by feline infectious peritonitis virus (FIPV), a biotype of feline coronavirus (FCoV).In contrast to feline uunipelti enteric coronavirus (FECV), which exclusively infects enterocytes and causes diarrhea, FIPV specifically targets macrophages, resulting
Matthias Helmschrott,1 Rasmus Rivinius,1 Thomas Bruckner,2 Hugo A Katus,1 Andreas O Doesch1 1Department of Cardiology, Angiology, Pneumology, 2Institute for Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany Background: A calcineurin inhibitor (CNI)-based immunosuppression combined with mammalian target of rapamycin inh